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      Intercampus Collaboration Yields a Successful Multi-PI R01 | Academic Integration
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      Many viruses are cloaked with an envelope derived from the host cell. To deliver the genome of the virus into the cell, viruses encode dedicated glycoproteins (fusion proteins) that are embedded in the envelope and which mediate the membrane fusion process. These fusion proteins come in three basic classes, with “class I” being found in such important viruses as influenza, HIV and paramyxoviruses. In these cases, it is well known that during virus entry a critical peptide is flipped out of the glycoprotein following proteolytic cleavage—to produce a so-called “external” fusion peptide.
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