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Mycophenolate Mofetil-Related Diarrhea and Beta-Glucuronidase Activity Following Kidney Transplantation - ATC Abstracts
*Purpose: The treatment of mycophenolate mofetil (MMF)-related diarrhea in kidney transplants recipients often involves dose reductions, which may result in less effective immunosuppression. We hypothesize that bacterial beta-glucuronidase activity, which is a key enzyme in MMF enterohepatic recirculation, is associated with diarrhea occurrence. *Methods: The ongoing Microbiome and Immunosuppression in Kidney Transplantation study used Mosio […]
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Mycophenolate Mofetil-Related Diarrhea and Beta-Glucuronidase Activity Following Kidney Transplantation - ATC Abstracts
*Purpose: The treatment of mycophenolate mofetil (MMF)-related diarrhea in kidney transplants recipients often involves dose reductions, which may result in less effective immunosuppression. We hypothesize that bacterial beta-glucuronidase activity, which is a key enzyme in MMF enterohepatic recirculation, is associated with diarrhea occurrence. *Methods: The ongoing Microbiome and Immunosuppression in Kidney Transplantation study used Mosio […]
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https://atcmeetingabstracts.com/abstract/mycophenolate-mofetil-related-diarrhea-and-beta-glucuronidase-activity-following-kidney-transplantationMycophenolate Mofetil-Related Diarrhea and Beta-Glucuronidase Activity Following Kidney Transplantation - ATC Abstracts
*Purpose: The treatment of mycophenolate mofetil (MMF)-related diarrhea in kidney transplants recipients often involves dose reductions, which may result in less effective immunosuppression. We hypothesize that bacterial beta-glucuronidase activity, which is a key enzyme in MMF enterohepatic recirculation, is associated with diarrhea occurrence. *Methods: The ongoing Microbiome and Immunosuppression in Kidney Transplantation study used Mosio […]
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