How can you avoid positive pressure when reconstituting antineoplastics? - Answers

To avoid positive pressure when reconstituting antineoplastics, ensure that you perform the procedure in a Class II biological safety cabinet (BSC) or compounding aseptic containment isolator (CACI) that maintains negative pressure. Always use appropriate personal protective equipment (PPE), including gloves and masks, to minimize exposure. Additionally, use a vented vial or a closed system transfer device (CSTD) to prevent the escape of aerosols and maintain containment during the process. Finally, follow established protocols and guidelines for handling hazardous drugs to ensure safety and compliance.